[Webmaster's clarification: for citations 1-10 see Cancer Legal Citations]

11. Abrams, Donald I., et al [2003]. Short-Term Effects of Cannabinoids in Patients with HIV-1 Infection: A Randomized, Placebo-Controlled Clinical Trial. Ann Intern Med. 2003 Aug 19;139(4):258-66.

12. Joy, Janet E.; Stanley J. Watson, Jr.; John A. Benson, Jr., Eds. Marijuana and Medicine: Assessing the Science Base. Washington, DC: Division of Neuroscience and Behavioral Health, Institute of Medicine. 1999.

13. British Medical Association [1997]. Therapeutic Uses of Cannabis. Harwood Academic Pub.

14. House of Lords, Select Committee on Science and Technology, [1998]. Cannabis: The Scientific and Medical Evidence. London, England: The Stationery Office, Parliament.

15. American Cancer Society [2003]. Cancer Facts and Figures 2003. http://www.cancer.org/downloads/STT/CAFF2003PWSecured.pdf

16. "Review of the Human Studies on the Medical Use of Marijuana," Dale Gieringer, Ph.D. (1996). http://norml.org/medical/medmj.studies.shtml. See state studies at http://www.drugpolicy.org/

17. W. Hall, et al., The Health and Psychological Consequences of Cannabis Use, Canberra, Australian Government Publishing Service (1994): 189. http://www.druglibrary.org/

18. Guzman M. [2003] Cannabinoids: potential anticancer agents. Nat Rev Cancer. 3(10): 745-55

19. Joy, op. cit., 259. (Chapter 4 of this report contains sections on nausea, vomiting, wasting syndrome and anorexia)

20. Doblin, Richard; Kleiman, Mark A. R. "Marijuana as Antiemetic Medicine: A Survey of Oncologists' Experiences and Attitudes." J Clin Oncol, 1991; 9: 1275-1290.

21. Knox, Richard A. "Study may undercut marijuana opponents - Report says THC did not cause cancer." Boston Globe. January 30, 1997. p. 1(A).

22. James, John S. "Medical Marijuana: Unpublished Federal Study Found THC- Treated Rats Lived Longer, Had Less Cancer." AIDS Treatment News. 1997. 263. http://www.immunet.org/

23. M. Guzman, "Cannabinoids: Potential Anticancer Agents," Nature Reviews Cancer 3, (2003) 745 -755.

24. Blazquez C, Casanova ML, Planas A, Del Pulgar TG, Villanueva C, Fernandez-Acenero MJ, Aragones J, Huffman JW, Jorcano JL, Guzman M. [2003] Inhibition of tumor angiogenesis by cannabinoids. FASEB J. 17(3): 529-31. Epub 2003 Jan 02.

25. Sanchez C, de Ceballos ML, del Pulgar TG, Rueda D, Corbacho C, Velasco G, Galve-Roperh I, Huffman JW, Ramon y Cajal S, Guzman M. [2001] Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor. Cancer Res. 61(15): 5784-9.

26 Casanova ML, Blazquez C, Martinez-Palacio J, Villanueva C, Fernandez- Acenero MJ, Huffman JW, Jorcano JL, Guzman M. [2003] Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. J Clin Invest. 111(1): 43-50

27. Jacobsson SO, Wallin T, Fowler CJ. [2001] Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors. J Pharmacol Exp Ther. 2001 Dec;299(3): 951-9.

28. I. Galve-Roperph et al. "Antitumoral action of cannabinoids: involvement of sustained ceramide accumulation of ERK activation." Nature Medicine 6 (2000): 313-319; ACM Bulletin. "THC destroys brain cancer in animal research." http://www.acmed.org/english/2000/eb000305.html

29. J. Benard. "Cannabinoids, among others, send malignant tumors to nirvana." Bull Cancer 87 (2000): 299-300.

30. Di Marzo V., et al. "Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells." Biochem J. 2001. 15(358): 249-55.

31. J. Molnar et al. "Membrane associated with antitumor effects of crocine-ginsenoside and cannabinoid derivatives." Anticancer Res 20 (2000): 861-867.

32. L. Ruiz et al. "Delta-9-tetrahydrocannabinol induces apoptosis in human prostate PC-3 cells via a receptor-independent mechanism." FEBS Letter 458 (1999): 400-404.

33. S. Baek et al. "Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells." Arch Pharm Res 21 (1998): 353-356.

34. L. Harris et al., "Anti-tumoral Properties of Cannabinoids," The Pharmacology of Marihuana, ed. M. Braude et al., 2 vols., New York: Raven Press (1976) 2: 773-776 as cited by L. Grinspoon et al., Marihuana: The Forbidden Medicine (second edition), New Haven, CT: Yale University Press (1997), 173.

35. "Toxicology and Carcinogenesis Studies of 1trans-delta-9-tetrahydrocannabinol in F344N/N Rats and BC63F1 Mice," National Institutes of Health National Toxicology Program, NIH Publication No. 97-3362 (November 1996).

36. L. De Petrocellis et al., The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation, Proceedings of the National Academy of Sciences 95 (1998): 8375-8380. http://www.pnas.org/cgi/content/ abstract/95/14/8375

37. "Pot Chemicals Might Inhibit Breast Tumors, Stroke Damage," Dallas Morning News, July 13, 1998.

38. Di Marzo V, Melck D, Orlando P, Bisogno T, Zagoory O, Bifulco M, Vogel Z, De Petrocellis L. [2001] Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells.Biochem J. 358(Pt 1):249-55

39. Portella G, Laezza C, Laccetti P, De Petrocellis L, Di Marzo V, Bifulco M [2003] Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis.FASEB J. 17(12): 1771-3. Epub 2003 Jul 03.

40. Mimeault M, Pommery N, Wattez N, Bailly C, Henichart JP. [2003] Antiproliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. Prostate. 56(1): 1-12.

41. Ligresti A, Bisogno T, Matias I, De Petrocellis L, Cascio MG, Cosenza V, D'argenio G, Scaglione G, Bifulco M, Sorrentini I, Di Marzo V. [2003] Possible endocannabinoid control of colorectal cancer growth. Gastroenterology. 125(3):677-87.

42. Gomez del Pulgar T, Velasco G, Sanchez C, Haro A, Guzman M. [2002] De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis. Biochem J. 363(Pt 1):183-8.

43. Gomez Del Pulgar T, De Ceballos ML, Guzman M, Velasco G. [2002] Cannabinoids protect astrocytes from ceramide-induced apoptosis through the phosphatidylinositol 3-kinase/protein kinase B pathway. J Biol Chem. 277(39):36527-33. Epub 2002 Jul 19.

44. Gonzalez S, Mauriello-Romanazzi G, Berrendero F, Ramos JA, Franzoni MF, Fernandez-Ruiz J. [2000] Decreased cannabinoid CB1 receptor mRNA levels and immunoreactivity in pituitary hyperplasia induced by prolonged exposure to estrogens. Pituitary. 3(4):221-6.

45. Pagotto U, Marsicano G, Fezza F, Theodoropoulou M, Grubler Y, Stalla J, Arzberger T, Milone A, Losa M, Di Marzo V, Lutz B, Stalla GK. [2001] Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids: first evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level. J Clin Endocrinol Metab. 86(6):2687-96

46. Rubovitch V, Gafni M, Sarne Y. [2002] The cannabinoid agonist DALN positively modulates L-type voltage-dependent calcium-channels in N18TG2 neuroblastoma cells. Brain Res Mol Brain Res. 101(1-2):93-102.

47. Bifulco M, Laezza C, Portella G, Vitale M, Orlando P, De Petrocellis L, Di Marzo V. [2001] Control by the endogenous cannabinoid system of ras oncogene- dependent tumor growth. FASEB J. 15(14):2745-7. Epub 2001 Oct 29.

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